Drug Discovery and Drug delivery system

Pre-formulation & Formulation Aspects

The physiochemical and mechanical properties of the medication are crucial in the production of the drug during pre-formulation investigations. It's vital to analyze how a protein behaves in solution under diverse physiological conditions when dealing with protein pre-formulation. When developing a drug, physio-chemical factors such as particle size, polymorphism, pH, and solubility should be taken into account because they affect bioavailability and activity. According to the formulation, the dosage should have a uniform appearance, a pleasing flavor, and good capsule dissolving capabilities